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RAMAS® Red List Professional consists of three integrated modules: RAMAS Red List 3.0, Temporal Analysis Module, and Spatial Analysis Module. RAMAS Red List 3.0 makes threatened species assessments, while the Temporal and Spatial Analysis Models estimate the parameters that are required as input data for a Red List assessment.

RAMAS Red List implements the IUCN Criteria for classifying species into threat categories while allowing explicit incorporation of uncertainties in the input data, which can be specified either as a number, a range of numbers, or a range plus a best estimate. RAMAS Red List propagates these uncertainties, and depending on the uncertainties, the resulting classification is often a single IUCN category, accompanied by a range of plausible categories.